The new body-horror movie "The Substance" is a wild time, It also took co-stars Demi Moore and Margaret Qualley way out of their comfort zones.

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Demi Moore gives the performance of her career in ‘The Substance,’ a gruesome horror epic that wickedly skewers our standards of female youth and beauty.

It's not long before Demi and her doppelganger are at each other's throats. Complications ensue when Sue is hired by Elisabeth's old boss (Quaid is scarily hilarious as Harvey) to star in a new workout show called "Pump It Up.

The actress stars alongside Margaret Qualley and Dennis Quaid in Coralie Fargeat’s gleefully grotesque movie about an aging celebrity who takes an experimental drug that gives her a younger self.

Coralie Fargeat’s sci-fi shocker follows the downward spiral of a 50-year-old movie star who resorts to drastic measures

The provocative new film “The Substance,” about an aging celebrity (Demi Moore) who takes an illicit drug to be young again, opened on September 20 following its May premiere in competition at the Cannes Film Festival,

The body horror nightmare story is sensual, unhinged, grotesque, and will have you howling with laughter. Demi Moore has never been better.