The San Francisco 49ers face the Los Angeles Rams at 1:25 p.m. PDT on Sunday, Sept. 22 at SoFi Stadium in Inglewood, CA.

The San Francisco 49ers will be without All-Pro tight end George Kittle for Sunday's game against the Los Angeles Rams.

Earlier this week, 49ers head coach Kyle Shanahan said he doesn't ask Brock Purdy to do too much on the field. That was an understatement. Shanahan doesn't all ...

but it’s the 49ers who still have premium players at left tackle (Trent Williams), receiver (Brandon Aiyuk), linebacker (Fred Warner), cornerback (Deommodore Lenoir) and defensive end (Nick Bosa).

Add Deebo Samuel to the San Francisco 49ers’ list of injuries woes. The wide receiver will miss “a couple of weeks” due ...

Jordan Mason might not be the best overall running back in the NFL right now, but it's hard to find one who carries the ball better than he does. The 49ers' cur ...

The San Francisco 49ers will open up their all-important NFC West schedule with a showdown against the Los Angeles Rams at ...

Injuries are an inherent part of the game of football, and the San Francisco 49ers are feeling the effects as they prepare ...