Brock Purdy has an opportunity to etch his name in the NFL record books when the 49ers face the Los Angeles Rams on Sunday at ...

San Francisco is already without All-Pro running back Christian McCaffrey, who went on injured reserve last week with ...

Brock Purdy is familiar with the feeling of victory at SoFi Stadium, having helped the San Francisco 49ers to a Week 2 win ...

Against the Rams, San Francisco will be without Kittle, running back Christian McCaffrey and receiver Deebo Samuel. McCaffrey ...

SANTA CLARA, Calif. (AP) — All-Pro tight end George Kittle will miss the San Francisco 49ers' game on Sunday against the Los ...

The San Francisco 49ers have been beset with injuries and tight end George Kittle can be added to the injury report. A ...

When NFL drafts come around, tailbacks are shunned as if the football they’re carrying is Limburger with a skin made of ...

San Francisco 49ers safety Talanoa Hufanga is poised to make his season debut on Sunday against the Los Angeles Rams.

The San Francisco 49ers will be without All-Pro tight end George Kittle for Sunday's game against the Los Angeles Rams.

Here are the latest predictions, picks, and odds for the 2024 NFL Week 3 matchup between the San Francisco 49ers vs. Los ...

The San Francisco 49ers will face the Los Angeles Rams on Sunday without wide receiver Deebo Samuel and running back ...

There may not be two teams more injured than the Los Angeles Rams and San Francisco 49ers, which will have a big impact on ...