A nearly forgotten third-string QB is the man 49ers fans really need to thank for Brock Purdy and George Kittle.

The San Francisco 49ers have another important division game on Sunday, but they may have to play without two of their biggest stars.

The Seattle Seahawks will visit the San Francisco 49ers in a key game in the NFC West race with both teams trying to catch ...

Listen in as players from the 49ers locker room shared their excitement for DB Deommodore Lenoir's five-year contract ...

The San Francisco 49ers kicked off their Week 11 practices with a handful off injury issues keeping players from practicing in full. In total, nine players were either absent from the session or ...

The San Francisco 49ers are preparing for their Week 11 contest against the Seattle Seahawks on Sunday at Levi's Stadium in ...

The San Francisco 49ers (5-4) have 11 players on the injury report, including George Kittle, ahead of their matchup against ...

The 49ers do not have tight end George Kittle (hamstring) and edge rusher Nick Bosa (hip) in Wednesday's practice.

San Francisco treaded water without Christian McCaffrey. Now that the NFL's reigning Offensive Player of the Year is back, it ...

San Francisco 49ers quarterback Brock Purdy was announced as NFL Slimetime's "Nickelodeon Valuable Player" for Week 10.